WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation
Abstract Background Apoptosis and oxidative stress are the main etiology of age related cataract (ARC). This article aims to investigate the role of WRN in lens epithelial cells (LECs). Methods We estimated the methylation level of WRN in anterior lens capsule tissues of ARC patients. SRA01/04 (LECs...
Saved in:
Main Authors: | Shengqun Jiang (Author), Jiansu Chen (Author) |
---|---|
Format: | Book |
Published: |
BMC,
2020-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Retraction Note to: WRN inhibits oxidative stress-induced apoptosis of human lensepithelial cells through ATM/p53 signaling pathway and its expression is downregulated by DNA methylation
by: Shengqun Jiang, et al.
Published: (2021) -
Anacardic acid inhibits pancreatic cancer cell growth, and potentiates chemotherapeutic effect by Chmp1A - ATM - p53 signaling pathway
by: Maiyon Park, et al.
Published: (2018) -
Cyclosporin A protects JEG-3 cells against oxidative stress-induced apoptosis by inhibiting the p53 and JNK/p38 signaling pathways
by: Bin He, et al.
Published: (2020) -
Recurrent skin ulcer cross-repair and sensory reconstruction in a WRN gene mutational patient
by: Jiqiang He, et al.
Published: (2018) -
Oxidative Stress and DNA Methylation in Prostate Cancer
by: Krishna Vanaja Donkena, et al.
Published: (2010)