Spectrum of microbial flora in diabetic foot ulcers
A prospective study was carried out on patients with diabetic foot lesions to determine their clinical characteristics, the spectrum of aerobic microbial flora and to assess their comparative <i>in vitro</i> susceptibility to the commonly used antibiotics. A total of 157 organisms (143 b...
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Main Authors: | , , , , |
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Format: | Book |
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Wolters Kluwer Medknow Publications,
2008-04-01T00:00:00Z.
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Summary: | A prospective study was carried out on patients with diabetic foot lesions to determine their clinical characteristics, the spectrum of aerobic microbial flora and to assess their comparative <i>in vitro</i> susceptibility to the commonly used antibiotics. A total of 157 organisms (143 bacteria and 14 fungi) were isolated and an average of 1.52 isolates per case was reported. Polymicrobial infection was found in 35% of the patients. In this study, <i>Pseudomonas aeruginosa</i> among the gram-negative (22%) and <i>Staphylococcus aureus</i> among the gram-positive (19%) were the predominantly isolated organisms, while <i>Candida</i> was the most predominantly isolated fungus. Antimicrobial sensitivity pattern of the isolates is discussed in detail. There was a linear increase in the prevalence of organisms with increase in Wagner′s grade. Neuropathy (76%) and peripheral vascular disease (57.28%) was a common feature among the patients. Poor glycemic control was found in 67% of the patients. Awareness about lower limb complications of diabetes was very low (23%) among the patients |
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Item Description: | 0377-4929 |