Paeoniflorin alleviates liver injury in hypercholesterolemic rats through the ROCK/AMPK pathway

• Main Authors: Tong Liu (Author), Ning Zhang (Author), Lingya Kong (Author), Sijie Chu (Author), Ting Zhang (Author), Guangdi Yan (Author), Donglai Ma (Author), Jun Dai (Author), Zhihong Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paeoniflorin (PF) is the main active component in Paeonia lactiflora Pall, and it has multiple effects. However, the precise mechanism of PF in hypercholesterolemia is unclear. In this study, rats were either fed a high-cholesterol diet (HCD) for 4 weeks to establish the hypercholesterolemic model o...