PFKFB3 deprivation attenuates the cisplatin resistance via blocking its autophagic elimination in colorectal cancer cells

• Main Authors: Qianqian Li (Author), Jianxing Ma (Author), Yaqin Zhang (Author), Fengyao Sun (Author), Wen Li (Author), Wenzhi Shen (Author), Zhiying Ai (Author), Changli Li (Author), Shanshan Wang (Author), Xiaonan Wei (Author), Siyuan Yan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 (PFKFB3) is highly expressed in several cancers and plays important roles during the whole pathological process of cancer. It is also involved in chemoresistance, while the intrinsic mechanism needs to be further revealed.Met...