Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• المؤلفون الرئيسيون: Grazyna Adler (مؤلف), Izabela Uzar (مؤلف), Amina Valjevac (مؤلف), Emina Kiseljakovic (مؤلف), Emir Mahmutbegovic (مؤلف), Nermin N. Salkic (مؤلف), Mateusz A. Adler (مؤلف), Nevena Mahmutbegovic (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...