Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Prif Awduron: Grazyna Adler (Awdur), Izabela Uzar (Awdur), Amina Valjevac (Awdur), Emina Kiseljakovic (Awdur), Emir Mahmutbegovic (Awdur), Nermin N. Salkic (Awdur), Mateusz A. Adler (Awdur), Nevena Mahmutbegovic (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...