Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Hauptverfasser: Grazyna Adler (Verfasst von), Izabela Uzar (Verfasst von), Amina Valjevac (Verfasst von), Emina Kiseljakovic (Verfasst von), Emir Mahmutbegovic (Verfasst von), Nermin N. Salkic (Verfasst von), Mateusz A. Adler (Verfasst von), Nevena Mahmutbegovic (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...