Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Κύριοι συγγραφείς: Grazyna Adler (Συγγραφέας), Izabela Uzar (Συγγραφέας), Amina Valjevac (Συγγραφέας), Emina Kiseljakovic (Συγγραφέας), Emir Mahmutbegovic (Συγγραφέας), Nermin N. Salkic (Συγγραφέας), Mateusz A. Adler (Συγγραφέας), Nevena Mahmutbegovic (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...