Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Päätekijät: Grazyna Adler (Tekijä), Izabela Uzar (Tekijä), Amina Valjevac (Tekijä), Emina Kiseljakovic (Tekijä), Emir Mahmutbegovic (Tekijä), Nermin N. Salkic (Tekijä), Mateusz A. Adler (Tekijä), Nevena Mahmutbegovic (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...