Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Príomhchruthaitheoirí: Grazyna Adler (Údar), Izabela Uzar (Údar), Amina Valjevac (Údar), Emina Kiseljakovic (Údar), Emir Mahmutbegovic (Údar), Nermin N. Salkic (Údar), Mateusz A. Adler (Údar), Nevena Mahmutbegovic (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...