Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• मुख्य लेखकों: Grazyna Adler (लेखक), Izabela Uzar (लेखक), Amina Valjevac (लेखक), Emina Kiseljakovic (लेखक), Emir Mahmutbegovic (लेखक), Nermin N. Salkic (लेखक), Mateusz A. Adler (लेखक), Nevena Mahmutbegovic (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...