Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• 主要な著者: Grazyna Adler (著者), Izabela Uzar (著者), Amina Valjevac (著者), Emina Kiseljakovic (著者), Emir Mahmutbegovic (著者), Nermin N. Salkic (著者), Mateusz A. Adler (著者), Nevena Mahmutbegovic (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...