Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Ngā kaituhi matua: Grazyna Adler (Author), Izabela Uzar (Author), Amina Valjevac (Author), Emina Kiseljakovic (Author), Emir Mahmutbegovic (Author), Nermin N. Salkic (Author), Mateusz A. Adler (Author), Nevena Mahmutbegovic (Author)
• Hōputu: Pukapuka
• I whakaputaina: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...