Genetic diversity of CYP3A5 and ABCB1 variants in East-Central and South European populations

• Asıl Yazarlar: Grazyna Adler (Yazar), Izabela Uzar (Yazar), Amina Valjevac (Yazar), Emina Kiseljakovic (Yazar), Emir Mahmutbegovic (Yazar), Nermin N. Salkic (Yazar), Mateusz A. Adler (Yazar), Nevena Mahmutbegovic (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2022-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background CYP3A5 enzyme encoded by CYP3A5 is important for drug metabolism in gut and liver, whereas P-glycoprotein by ABCB1, is an ATP-dependent drug efflux pump which exports endo- and exogenous substances outside the cell. Aim The study was to assess the prevalence of CYP3A5 alleles: *1, *2, *3,...