Parenteral Lipid-Based Nanoparticles for CNS Disorders: Integrating Various Facets of Preclinical Evaluation towards More Effective Clinical Translation

• Auteurs principaux: Tanja Ilić (Auteur), Jelena B. Đoković (Auteur), Ines Nikolić (Auteur), Jelena R. Mitrović (Auteur), Ivana Pantelić (Auteur), Snežana D. Savić (Auteur), Miroslav M. Savić (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Contemporary trends in combinatorial chemistry and the design of pharmaceuticals targeting brain disorders have favored the development of drug candidates with increased lipophilicity and poorer water solubility, with the expected improvement in delivery across the blood-brain barrier (BBB). The gro...