Severe Periodontal Disease Associated with Long-Term Treatment with Intravenous Immunoglobulin

• Main Authors: Jôice Dias Corrêa (Author), Amanda Leal Rocha (Author), Lidiane Cristina Machado Costa (Author), Denise Travassos (Author), Wagner Henriques Castro (Author), Gustavo Pompermaier Garlet (Author), Rodrigo Santiago Gomez (Author), Antônio Lúcio Teixeira (Author), Tarcília Aparecida Silva (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Intravenous immunoglobulin (IVIG) is used in the treatment of neuropathy. This case report presents, for the first time, a patient with severe periodontal destruction after chronic therapy with IVIG. The patient reported having extracted his maxillary anterior teeth himself due to high mobility. Clinical examination and radiographic images show a generalized and severe periodontitis. No significant alterations in genetic or microbiological features were observed. The present case suggests that periodontal disease aggravation could be considered a new adverse effect of IVIG therapy. Postulated mechanisms are immune complexes formation, complement activation, and a direct effect in osteoclasts. In conclusion, it is important that patients that will receive IVIG treatment underwent dental evaluation.

Item Description

2090-6447
2090-6455
10.1155/2014/860804