Delivery Strategies for Colchicine as a Critical Dose Drug: Reducing Toxicity and Enhancing Efficacy

• Những tác giả chính: Yaran Lei (Tác giả), Yulu Yang (Tác giả), Guobao Yang (Tác giả), Ao Li (Tác giả), Yang Yang (Tác giả), Yuli Wang (Tác giả), Chunsheng Gao (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2024-02-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Colchicine (COL), a widely used natural drug, has potent anti-inflammatory effects; however, as a narrow therapeutic index drug, its clinical application is limited by its serious gastrointestinal adverse effects, and only oral formulations are currently marketed worldwide. Recent studies have shown...