Vitamin D receptor polymorphisms and vitamin D insufficiency are not associated with sepsis in critically ill children: a case-control study

Highlights • Vitamin D level was low in both pediatric septic ICU patients and age- and sex-matched healthy controls. • Vitamin D levels were unaffected by VDR polymorphisms, and their distribution was similar in both groups. • Neither the need for mechanical ventilation or inotropic treatment nor t...

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Main Authors: Iman Shaheen (Author), Rasha Afifi (Author), Nelly Abulata (Author), Reham Aboukhalil (Author), Basant Meligy (Author), HebatAllah F. Algebaly (Author), Omnia Y. Abd El Dayem (Author)
Format: Book
Published: SpringerOpen, 2022-12-01T00:00:00Z.
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Summary:Highlights • Vitamin D level was low in both pediatric septic ICU patients and age- and sex-matched healthy controls. • Vitamin D levels were unaffected by VDR polymorphisms, and their distribution was similar in both groups. • Neither the need for mechanical ventilation or inotropic treatment nor the sepsis outcome was impacted by vitamin D or VDR polymorphisms.
Item Description:10.1186/s43054-022-00130-1
2090-9942