Effect of perindopril or leucine on physical performance in older people with sarcopenia: the LACE randomized controlled trial

• Main Authors: The LACE study group (Author), Marcus Achison (Author), Simon Adamson (Author), Asangaedem Akpan (Author), Terry Aspray (Author), Alison Avenell (Author), Margaret M. Band (Author), Tufail Bashir (Author), Louise A. Burton (Author), Vera Cvoro (Author), Peter T. Donnan (Author), Gordon W. Duncan (Author), Jacob George (Author), Adam L. Gordon (Author), Celia L. Gregson (Author), Adrian Hapca (Author), Emily Henderson (Author), Cheryl Hume (Author), Thomas A. Jackson (Author), Paul Kemp (Author), Simon Kerr (Author), Alixe Kilgour (Author), Veronica Lyell (Author), Tahir Masud (Author), Andrew McKenzie (Author), Emma McKenzie (Author), Harnish Patel (Author), Kristina Pilvinyte (Author), Helen C. Roberts (Author), Christos Rossios (Author), Avan A. Sayer (Author), Karen T. Smith (Author), Roy L. Soiza (Author), Claire J. Steves (Author), Allan D. Struthers (Author), Deepa Sumukadas (Author), Divya Tiwari (Author), Julie Whitney (Author), Miles D. Witham (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background This trial aimed to determine the efficacy of leucine and/or perindopril in improving physical function in older people with sarcopenia. Methods Placebo‐controlled, parallel group, double‐blind, randomized two‐by‐two factorial trial. We recruited adults aged ≥ 70 years with sarco...