Determinants of mortality in neonatal intestinal obstruction in Ile Ife, Nigeria

<b>Background:</b> Neonatal intestinal obstruction (NIO) is a common cause of mortality. This study determined the causes of mortality in patients with NIO at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile Ife. <b> Patients and Methods:</b> Records of...

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Main Authors: Ademuyiwa A (Author), Sowande O (Author), Ijaduola T (Author), Adejuyigbe O (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2009-01-01T00:00:00Z.
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Summary:<b>Background:</b> Neonatal intestinal obstruction (NIO) is a common cause of mortality. This study determined the causes of mortality in patients with NIO at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile Ife. <b> Patients and Methods:</b> Records of all cases of NIO managed at OAUTHC between January 1996 and December 2005 were retrospectively reviewed and the possible factors that may result in mortality were analysed. <b> Results:</b> Sixty-three neonates with intestinal obstruction were managed, representing 24.3&#x0025; of the neonatal admissions during the study period. Forty-two were males and 21 were females (M:F = 2:1). The majority (71.4&#x0025;) of the patients presented within the first week of life. Anorectal malformation constituted 57.1&#x0025; of the causes of NIO. Other causes included Hirschsprung&#x2032;s disease, duodenal atresia, intestinal malrotation with midgut volvulus and jejunal atresia. There were 18 deaths, with a mortality rate of 28.6&#x0025;. Reoperation, postoperative bleeding and peroperative sepsis were significant determinants of mortality. <b> Conclusion:</b> NIO is associated with significant mortality in our centre. Repeat surgery, postoperative bleeding and sepsis were the significant factors that contributed to mortality in NIO.
Item Description:0189-6725