Exploring the interaction between epidermal growth factor receptor tyrosine kinase and some of the synthesized inhibitors using combination of in-silico and in-vitro cytotoxicity methods
Quinazoline derivatives are potent inhibitors of human epidermal growth factor receptor (EGFR) as anticancer agents. In this study, the cytotoxic effects of a new series of synthesized quinazoline derivatives were evaluated using MTT assay against MCF-7 and HT-29 cell lines. Using molecular docking,...
שמור ב:
Main Authors: | Rezvan Rezaee Nasab (Author), Mahboubeh Mansourian (Author), Farshid Hassanzadeh (Author), Mohsen Shahlaei (Author) |
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פורמט: | ספר |
יצא לאור: |
Wolters Kluwer Medknow Publications,
2018-01-01T00:00:00Z.
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