Acehytisine suppresses atrial fibrillation in rats with dilated atria caused by chronic volume overload

• Main Authors: Xin Cao (Author), Yoshinobu Nagasawa (Author), Chengshun Zhang (Author), Hanxiao Zhang (Author), Megumi Aimoto (Author), Akira Takahara (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atrial dilation is an independent risk factor for the development of atrial fibrillation (AF) and modulates the efficacy of anti-AF drugs, leading to the unsatisfactory control of AF. Pre-clinical studies showed anti-AF effects of acehytisine, a multi-ion channel inhibitor, in atria without structur...