Measurement, analysis and prediction of amoxicillin oral dose stability from integrated molecular description approach and accelerated predictive stability (APS)

• Main Authors: Merienne Camille (Author), Marchand Chloe (Author), Filali Samira (Author), Salmon Damien (Author), Pivot Christine (Author), Pirot Fabrice (Author)
• Format: Book
• Published: De Gruyter, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stability of low amoxicillin oral dosage form (5 mg) used in reintroduction drug test was not fully documented. Furthermore, the impact of (1) salt moiety of amoxicillin and (2) amoxicillin - excipient interactions upon the antibiotic formulation stability during the storage was not characterized so...