A Case Report of Meigs’ Syndrome Caused by Ovarian Fibrothecoma with High Levels of CA125

Liqin Yuan, Lin Cui, Jie Wang, Li Gong Department of Gynecology, Rizhao People's Hospital, Rizhao, Shandong Province, 276800, People's Republic of ChinaCorrespondence: Li Gong, Rizhao People's Hospital, Rizhao, Shandong Province, 276800, People's Republic of China, Tel +86-186633...

Full description

Saved in:
Bibliographic Details
Main Authors: Yuan L (Author), Cui L (Author), Wang J (Author), Gong L (Author)
Format: Book
Published: Dove Medical Press, 2024-03-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_606bd9fce0c842f3bbb9cbb2c44a37bb
042 |a dc 
100 1 0 |a Yuan L  |e author 
700 1 0 |a Cui L  |e author 
700 1 0 |a Wang J  |e author 
700 1 0 |a Gong L  |e author 
245 0 0 |a A Case Report of Meigs’ Syndrome Caused by Ovarian Fibrothecoma with High Levels of CA125 
260 |b Dove Medical Press,   |c 2024-03-01T00:00:00Z. 
500 |a 1179-1411 
520 |a Liqin Yuan, Lin Cui, Jie Wang, Li Gong Department of Gynecology, Rizhao People's Hospital, Rizhao, Shandong Province, 276800, People's Republic of ChinaCorrespondence: Li Gong, Rizhao People's Hospital, Rizhao, Shandong Province, 276800, People's Republic of China, Tel +86-18663351821, Email gongli0768@163.comPurpose: Meigs' syndrome is a rare gynecological disease characterized by the triad of benign ovarian tumor, ascites, and pleural effusion. Ovarian malignancies should be highly suspected in a postmenopausal woman with a pelvic mass, ascites, hydrothorax, and an elevated carbohydrate antigen 125 (CA125) level. It can be challenging to make a preoperative diagnosis of Meigs' syndrome. In this report, we present a case of Meigs' syndrome caused by an ovarian fibrothecoma and review the relevant literature to raise awareness and avoid misdiagnosis.Case Presentation: An 82-year-old woman with a 2-week history of abdominal distension was admitted to the Department of Gynecology. Ultrasound and thoracoabdominal computed tomography scans showed a left-sided hypoechoic mass in the pelvic cavity with bilateral pleural effusion and massive ascites. The CA125 concentration was 1040 U/mL (normal, 0- 35 U/mL). With a working diagnosis of ovarian malignancy, the patient underwent ultrasound-guided fine-needle puncture of the pelvic mass and paracentesis to drain the ascites. The fine-needle puncture and paracentesis fluid analysis results revealed that the ascites did not contain any tumor cells, and the pelvic mass was identified as a spindle cell tumor. Immunohistochemistry confirmed that it was a sex-cord stromal tumor. Total abdominal hysterectomy and bilateral adnexectomy were performed under general anesthesia. The pathology results confirmed the mass to have been an ovarian fibrothecoma. At the 2-month postoperative follow-up, the ascites and hydrothorax had resolved and not recurred, and the CA125 level was normal.Conclusion: Despite the high suspicion of ovarian carcinoma in postmenopausal women presenting with pelvic mass, ascites, pleural effusion, and elevated CA125, Meigs' syndrome should be considered.Keywords: Meigs' syndrome, ascites, pleural effusion, CA125, ovarian fibrothecoma, ovarian cancer 
546 |a EN 
690 |a meigs' syndrome 
690 |a ascites 
690 |a pleural effusion 
690 |a ca125 
690 |a ovarian fibrothecoma 
690 |a ovarian cancer 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n International Journal of Women's Health, Vol Volume 16, Pp 519-525 (2024) 
787 0 |n https://www.dovepress.com/a-case-report-of-meigs-syndrome-caused-by-ovarian-fibrothecoma-with-hi-peer-reviewed-fulltext-article-IJWH 
787 0 |n https://doaj.org/toc/1179-1411 
856 4 1 |u https://doaj.org/article/606bd9fce0c842f3bbb9cbb2c44a37bb  |z Connect to this object online.