Dietary Behavior of <i>Drosophila melanogaster</i> Fed with Genetically-Modified Corn or Roundup^®

• Main Authors: Raquel Elias (Author), Becky Talyn (Author), Erik Melchiorre (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

With the rise in concern about GMOs and pesticides on human health, we have utilized <i>Drosophila melanogaster</i> as a model organism for understanding the effects of Roundup-Ready^® GMO diets on health. We recorded dietary behavior during and after exposure to a medium containing GMO or non-GMO corn, Roundup^® in organic corn medium, and sucrose with or without one of the two Roundup^® formulations. No differences in behavior were observed when <i>Drosophila</i> were exposed to a medium containing Roundup-Ready^® GMO or non-GMO corn. <i>Drosophila</i> can detect and refrain from eating sucrose containing one Roundup^® formulation, Ready-to-Use, which contains pelargonic acid in addition to glyphosate as an active ingredient. <i>Drosophila</i> exhibited dose-dependent increased consumption of sucrose alone after exposure to a medium containing either Roundup^® formulation. This may indicate that flies eating a medium with Roundup^® eat less and were thus hungrier when then given sucrose solution; that a medium with Roundup^® is more difficult to digest; or that a medium with Roundup^® is less nutritious, as would be the case if nutritionally important microbes grew on control medium, but not one containing Roundup^®.

Item Description

10.3390/jox11040014
2039-4713
2039-4705