Selumetinib - a potential small molecule inhibitor for osteoarthritis treatment
Objectives: Osteoarthritis (OA) is a common disease that mainly manifests as inflammation and destruction of cartilage and subchondral bone. Recently, necroptosis has been reported to play an important role in the development of OA. Selumetinib displays a contrasting expression pattern to necroptosi...
Saved in:
Main Authors: | Xiaohang Zheng (Author), Jianxin Qiu (Author), Wenjun Pan (Author), Yuhang Gong (Author), Weikang Zhang (Author), Ting Jiang (Author), Lihua Chen (Author), Weifu Chen (Author), Zhenghua Hong (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2022-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Platelet-Derived Growth Factor-BB Inhibits Intervertebral Disc Degeneration via Suppressing Pyroptosis and Activating the MAPK Signaling Pathway
by: Weikang Zhang, et al.
Published: (2022) -
Identification of the Major Degradation Pathways of Selumetinib
by: Tahar Sif eddine Bouchema, et al.
Published: (2022) -
Paroxetine Attenuates Chondrocyte Pyroptosis and Inhibits Osteoclast Formation by Inhibiting NF-κB Pathway Activation to Delay Osteoarthritis Progression
by: Zheng X, et al.
Published: (2023) -
Current Insights Into the Maintenance of Structure and Function of Intervertebral Disc: A Review of the Regulatory Role of Growth and Differentiation Factor-5
by: Bin Lv, et al.
Published: (2022) -
Polyphyllin VII increases sensitivity to gefitinib by modulating the elevation of P21 in acquired gefitinib resistant non-small cell lung cancer
by: Honggang Wang, et al.
Published: (2017)