Cancer cachexia impairs neural respiratory drive in hypoxia but not hypercapnia

• Main Authors: Daryl P. Fields (Author), Brandon M. Roberts (Author), Alec K. Simon (Author), Andrew R. Judge (Author), David D. Fuller (Author), Gordon S. Mitchell (Author)
• Format: Book
• Published: Wiley, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer cachexia is an insidious process characterized by muscle atrophy with associated motor deficits, including diaphragm weakness and respiratory insufficiency. Although neuropathology contributes to muscle wasting and motor deficits in many clinical disorders, neural involvem...