Identification of therapeutic targets for osteosarcoma by integrating single-cell RNA sequencing and network pharmacology

• Main Authors: Yan Wang (Author), Di Qin (Author), Yiyao Gao (Author), Yunxin Zhang (Author), Yao Liu (Author), Lihong Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Osteosarcoma (OS) is a common primary tumor with extensive heterogeneity. In this study, we used single-cell RNA sequencing (scRNA-seq) and network pharmacology to analyze effective targets for Osteosarcoma treatment.Methods: The cell heterogeneity of the Osteosarcoma single-cell dataset...