Pharmacokinetic variability of factor VIII concentrates in Chinese pediatric patients with moderate or severe hemophilia A

• Main Authors: Zhenping Chen (Author), Kun Huang (Author), Gang Li (Author), Yingzi Zhen (Author), Xinyi Wu (Author), Ai Di (Author), Guoqing Liu (Author), Zekun Li (Author), Iorio Alfonso (Author), Runhui Wu (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Importance The use of factor VIII (FVIII) concentrates under pharmacokinetic (PK) guidance has become the main approach for treatment of hemophilia. However, limited PK research has been conducted in Chinese pediatric patients. Objective To investigate the PK parameters of various FVIII con...