IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis.
BACKGROUND: Chagas disease is a neglected disease caused by the intracellular parasite Trypanosoma cruzi. Around 30% of the infected patients develop chronic cardiomyopathy or megasyndromes, which are high-cost morbid conditions. Immune response against myocardial self-antigens and exacerbated Th1 c...
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Main Authors: | Paulo Marcos da Matta Guedes (Author), Fredy R S Gutierrez (Author), Flavia L Maia (Author), Cristiane M Milanezi (Author), Grace K Silva (Author), Wander R Pavanelli (Author), João S Silva (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2010-01-01T00:00:00Z.
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