An Updated Review on the Multifaceted Therapeutic Potential of <i>Calendula officinalis</i> L.

• Main Authors: Kiran Shahane (Author), Madhuri Kshirsagar (Author), Srushti Tambe (Author), Divya Jain (Author), Srutee Rout (Author), Maria Karolina Martins Ferreira (Author), Suraj Mali (Author), Purnima Amin (Author), Prem Prakash Srivastav (Author), Jorddy Cruz (Author), Rafael Rodrigues Lima (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<i>Calendula officinalis</i> Linn. (CO) is a popular medicinal plant from the plant kingdom's Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO's molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments.

Item Description

10.3390/ph16040611
1424-8247