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Ifosfamide-Induced Metabolic Encephalopathy in 2 Patients With Cutaneous T-Cell Lymphoma Successfully Treated With Methylene Blue

Ifosfamide, an alkylating agent used in cancer treatments, can cause neurotoxicity. The clinical presentation can range from mild symptoms such as acute confusion to non-convulsive seizures, severe irreversible coma, and death. The benefit of methylene blue use in treating ifosfamide-induced metabol...

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Bibliographic Details
Main Authors: Anusha Vakiti MD (Author), Ravi Pilla MD (Author), Muhamad Alhaj Moustafa MD (Author), Jacinth J. Joseph MD (Author), Aarthi G. Shenoy MD (Author)
Format: Book
Published: SAGE Publishing, 2018-07-01T00:00:00Z.
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Summary:Ifosfamide, an alkylating agent used in cancer treatments, can cause neurotoxicity. The clinical presentation can range from mild symptoms such as acute confusion to non-convulsive seizures, severe irreversible coma, and death. The benefit of methylene blue use in treating ifosfamide-induced metabolic encephalopathy is not well established. In this article, we present 2 cases of ifosfamide-induced metabolic encephalopathy responsive to methylene blue treatment.
Item Description:2324-7096
10.1177/2324709618786769

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