CRF-R1 Antagonist Treatment Exacerbates Circadian Corticosterone Secretion under Chronic Stress, but Preserves HPA Feedback Sensitivity
Despite promising initial reports, corticotropin-releasing factor receptor type-1 (CRF-R1) antagonists have mostly failed to display efficacy in clinical trials for anxiety or depression. Rather than broad-spectrum antidepressant/anxiolytic-like drugs, they may represent an 'antistress' so...
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Main Authors: | Yadira Ibarguen-Vargas (Author), Samuel Leman (Author), Rupert Palme (Author), Catherine Belzung (Author), Alexandre Surget (Author) |
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Format: | Book |
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MDPI AG,
2021-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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