Electrocardiographic Effects of a Supratherapeutic Dose of WCK 2349, a Benzoquinolizine Fluoroquinolone

• Main Authors: Jay W. Mason (Author), Rakesh Chugh (Author), Anasuya Patel (Author), Ranjeet Gutte (Author), Ashima Bhatia (Author)
• Format: Book
• Published: Wiley, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to measure the electrocardiographic (ECG) effects of WCK 2349 (the L‐alanine ester prodrug of levonadifloxacin) at a supratherapeutic oral dose of 2,600 mg. A total of 48 healthy volunteers were randomized to treatment with placebo, WCK 2349, or oral moxifloxacin, 400 m...