Generating Anti-TIGIT and CD155 Monoclonal Antibodies for Tumor Immunotherapy

Many studies have confirmed that the human poliovirus receptor (PVR; CD155) is related to tumor cell migration, invasion, and thus tumor progression. A PVR receptor binds its ligand T cell Ig and the ITIM domain (TIGIT) to inhibit the function of T and NK cells, thereby allowing tumors to evade immu...

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Main Authors: Yu-Hang Duan (Author), Yan-lin Bian (Author), Jian-Wei Zhu (Author)
Format: Knjiga
Izdano: Georg Thieme Verlag KG, 2022-09-01T00:00:00Z.
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