In Vitro and In Vivo Evaluation of Composite Oral Fast Disintegrating Film: An Innovative Strategy for the Codelivery of Ranitidine HCl and Flurbiprofen

• Main Authors: Aisha Rashid (Author), Syed Haroon Khalid (Author), Muhammad Irfan (Author), Sajid Asghar (Author), Waleed Y. Rizg (Author), Fahad Y. Sabei (Author), Eman Alfayez (Author), Hanaa Alkharobi (Author), Awaji Y. Safhi (Author), Khaled M. Hosny (Author), Muhammad Sohail Arshad (Author), Ikram Ullah Khan (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we evaluate the feasibility of co-loading plain ranitidine hydrochloride (RHCl) and microencapsulated flurbiprofen (FBP) in a Lycoat^® RS780-based oral fast disintegrating film (ODF). These films were developed by the solvent casting method to minimize the adverse effects...