<i>Mangifera indica</i> L. Leaves as a Potential Food Source of Phenolic Compounds with Biological Activity

It is well recognized that functional foods rich in antioxidants and antiinflammation agents including polyphenols, probiotics/prebiotics, and bioactive compounds have been found to have positive effects on the aging process. In particular, fruits play an important role in regular diet, promoting go...

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Main Authors: Giuseppe Sferrazzo (Author), Rosa Palmeri (Author), Cristina Restuccia (Author), Lucia Parafati (Author), Laura Siracusa (Author), Mariarita Spampinato (Author), Giuseppe Carota (Author), Alfio Distefano (Author), Michelino Di Rosa (Author), Barbara Tomasello (Author), Angelita Costantino (Author), Massimo Gulisano (Author), Giovanni Li Volti (Author), Ignazio Barbagallo (Author)
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Published: MDPI AG, 2022-06-01T00:00:00Z.
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001 doaj_6568dbda0a3f4f7a971dba040afaeafe
042 |a dc 
100 1 0 |a Giuseppe Sferrazzo  |e author 
700 1 0 |a Rosa Palmeri  |e author 
700 1 0 |a Cristina Restuccia  |e author 
700 1 0 |a Lucia Parafati  |e author 
700 1 0 |a Laura Siracusa  |e author 
700 1 0 |a Mariarita Spampinato  |e author 
700 1 0 |a Giuseppe Carota  |e author 
700 1 0 |a Alfio Distefano  |e author 
700 1 0 |a Michelino Di Rosa  |e author 
700 1 0 |a Barbara Tomasello  |e author 
700 1 0 |a Angelita Costantino  |e author 
700 1 0 |a Massimo Gulisano  |e author 
700 1 0 |a Giovanni Li Volti  |e author 
700 1 0 |a Ignazio Barbagallo  |e author 
245 0 0 |a <i>Mangifera indica</i> L. Leaves as a Potential Food Source of Phenolic Compounds with Biological Activity 
260 |b MDPI AG,   |c 2022-06-01T00:00:00Z. 
500 |a 10.3390/antiox11071313 
500 |a 2076-3921 
520 |a It is well recognized that functional foods rich in antioxidants and antiinflammation agents including polyphenols, probiotics/prebiotics, and bioactive compounds have been found to have positive effects on the aging process. In particular, fruits play an important role in regular diet, promoting good health and longevity. In this study, we investigated on biological properties of extract obtained from <i>Mangifera indica</i> L. leaves in preclinical in vitro models. Specifically, the profile and content of bioactive compounds, the antimicrobial potential toward food spoilage and pathogenic bacterial species, and the eventually protective effect in inflammation were examined. Our findings revealed that MLE was rich in polyphenols, showing a content exclusively in the subclass of benzophenone/xanthone metabolites, and these phytochemical compounds demonstrated the highest antioxidant capacity and greatest in vitro antibacterial activity toward different bacterial species such as <i>Bacillus cereus</i>, <i>B. subtilis</i>, <i>Pseudomonas fluorescens</i>, <i>Staphylococcus aureus</i>, and <i>St. haemolyticus</i>. Furthermore, our data showed an in vitro anti-inflammatory, antioxidant, and antifibrotic activity. 
546 |a EN 
690 |a <i>Mangifera indica</i> L. 
690 |a bioactive compound 
690 |a antimicrobial 
690 |a antioxidant 
690 |a antifibrotic 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Antioxidants, Vol 11, Iss 7, p 1313 (2022) 
787 0 |n https://www.mdpi.com/2076-3921/11/7/1313 
787 0 |n https://doaj.org/toc/2076-3921 
856 4 1 |u https://doaj.org/article/6568dbda0a3f4f7a971dba040afaeafe  |z Connect to this object online.