Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluation
The antibiotic resistance of methicillin-resistant Staphylococcus aureus (MRSA) is attributable to the expression of the high molecular mass transpeptidase enzyme, penicillin-binding protein 2a (PBP2a), an enzyme that catalyzes the cross-linking reaction step in the cell wall biosynthesis in the fac...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
Ain Shams University,
2019-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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