Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report

• Main Authors: Tanaka Motoyuki (Author), Setoguchi Takao (Author), Ishidou Yasuhiro (Author), Arishima Yoshiya (Author), Hirotsu Masataka (Author), Saitoh Yoshinobu (Author), Nakamura Shunsuke (Author), Kakoi Hironori (Author), Nagano Satoshi (Author), Yokouchi Masahiro (Author), Kamizono Junichi (Author), Komiya Setsuro (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<p>Abstract</p> <p>We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occurrence of femoral neck fracture. Orthopedic surgeons should be aware of osteomalacia and pathological hip fracture caused by drug-induced renal dysfunction, which results in Fanconi's syndrome.</p> <p>Virtual slides</p> <p>The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1600344696739249</p>

Item Description

10.1186/1746-1596-7-108
1746-1596