First- and Second-trimester Down Syndrome Screening: Current Strategies and Clinical Guidelines

• Main Authors: Sheng-Wen Shaw (Author), Jenn-Jeih Hsu (Author), Chien-Nan Lee (Author), Ching-Hua Hsiao (Author), Chih-Ping Chen (Author), T'sang-T'ang Hsieh (Author), Po-Jen Cheng (Author)
• Format: Book
• Published: Elsevier, 2008-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Down syndrome (DS) is the most common human disease caused by a structural chromosome defect. The original screening test for DS was maternal age or a history of a previously affected infant. Maternal serum screening has been incorporated into routine prenatal checkup in Taiwan since 1994. We used f...