Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks
Abstract Background Bacterial lipopolysaccharide (LPS) induces a multi-organ, Toll-like receptor 4 (TLR4)-dependent acute inflammatory response. Methods Using network analysis, we defined the spatiotemporal dynamics of 20, LPS-induced, protein-level inflammatory mediators over 0-48 h in the heart, g...
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Main Authors: | Ruben Zamora (Author), Sangeeta Chavan (Author), Theodoros Zanos (Author), Richard L. Simmons (Author), Timothy R. Billiar (Author), Yoram Vodovotz (Author) |
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Format: | Book |
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BMC,
2021-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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