Antitumor Activity of (2E,5Z)-5-(2-Hydroxybenzylidene)-2-((4-phenoxyphenyl)imino) thiazolidin-4-one, a Novel Microtubule-Depolymerizing Agent, in U87MG Human Glioblastoma Cells and Corresponding Mouse Xenograft Model
Glioblastoma is the most lethal brain cancer. In spite of intensive therapy, the prognosis of patients with glioblastoma is very poor. To discover novel therapeutic agents, we screened a combinatorial compound library containing 372 thiazolidinone compounds using U87MG human glioblastoma cells. (2E,...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2013-01-01T00:00:00Z.
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