Spectrophotometric Determination of Mesalazine Via Arsenazo III- Cerium(III) Reaction
Abstract<br /> A simple and sensitive spectrophotometric method has been developed for the determination of mesalazine (5-aminosalicylic acid) in pure form and in its pharmaceutical preparation(capsule). The method is based on the oxidation-reduction reaction between mesalazine and cerium (IV)...
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College of Education for Pure Sciences,
2011-03-01T00:00:00Z.
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| 001 | doaj_66f1c1e8c9da44b59d02d2989ec9960d | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Zeena Z. Al-Abdaly |e author |
| 245 | 0 | 0 | |a Spectrophotometric Determination of Mesalazine Via Arsenazo III- Cerium(III) Reaction |
| 260 | |b College of Education for Pure Sciences, |c 2011-03-01T00:00:00Z. | ||
| 500 | |a 1812-125X | ||
| 500 | |a 2664-2530 | ||
| 500 | |a 10.33899/edusj.2011.51507 | ||
| 520 | |a Abstract<br /> A simple and sensitive spectrophotometric method has been developed for the determination of mesalazine (5-aminosalicylic acid) in pure form and in its pharmaceutical preparation(capsule). The method is based on the oxidation-reduction reaction between mesalazine and cerium (IV) ion, then reaction of cerium(III) with arsenazo III reagent in acidic medium to produce a green-blue complex, which is stable, water soluble and has a maximum absorption at 654 nm with a molar absorptivity of 2.103×105 l.mol-1.cm -1. Beerُ s law is obeyed in the concentration range of 0.5 to 14 µg of mesalazine in a final volume of 25 ml. The proposed method has been applied successfully for determination of mesalazine in pharmaceutical preparation (capsule). | ||
| 546 | |a AR | ||
| 546 | |a EN | ||
| 690 | |a spectrophotometry | ||
| 690 | |a mesalazine | ||
| 690 | |a arsenazo | ||
| 690 | |a cerium | ||
| 690 | |a Education | ||
| 690 | |a L | ||
| 690 | |a Science (General) | ||
| 690 | |a Q1-390 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n مجلة التربية والعلم, Vol 24, Iss 1, Pp 13-21 (2011) | |
| 787 | 0 | |n https://edusj.mosuljournals.com/article_51507_99ccd6bddb557c83385ed403f0683b64.pdf | |
| 787 | 0 | |n https://doaj.org/toc/1812-125X | |
| 787 | 0 | |n https://doaj.org/toc/2664-2530 | |
| 856 | 4 | 1 | |u https://doaj.org/article/66f1c1e8c9da44b59d02d2989ec9960d |z Connect to this object online. |