Anti-<i>Salmonella</i> and Antibiofilm Potency of <i>Salvia officinalis</i> L. Essential Oil against Antibiotic-Resistant <i>Salmonella enterica</i>

• Main Authors: Samy Selim (Author), Mohammed S. Almuhayawi (Author), Hussain Alqhtani (Author), Soad K. Al Jaouni (Author), Fayez M. Saleh (Author), Mona Warrad (Author), Nashwa Hagagy (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Raw milk is a significant vehicle for the transmission of different infections. In the present study, we focused on <i>Salmonella enterica</i> from raw milk and its resistance to various antibacterial drugs. Furthermore, we have investigated the antimicrobial and antibiofilm effects of essential oil (EO) obtained from <i>Salvia officinalis</i> L. leaves that were collected from the Aljouf region, Saudi Arabia, against <i>S. enterica</i>. One-dozen strains of <i>S. enterica</i> were found in a batch of a hundred milk samples, and those <i>S. enterica</i> strains were shown to be resistant to several antibiotics, particularly the β-lactam group of antimicrobial drugs. Against multidrug-resistant <i>S. enterica</i>, the inhibitory zones for EO from <i>S. officinalis</i> leaves were found to be 21 mm in diameter. <i>S. officinalis</i> EO at 5% concentration showed a remarkable in vitro inhibitory activity toward the biofilm growth of different <i>S. enterica</i> isolates. Analysis of EO by GC-MS identified 21 distinct components, accounting for 89.94% of the total oil component. The most prominent compounds were 1,8-cineole (39.18%), β-caryophyllene (12.8%), and α--terpineol (10.3%). Taken together, our results unequivocally confirm that the <i>S. officinalis</i> EOs exert numerous bioactivities. Thus, the well-deserved attention on <i>S. officinalis</i> EO usage as a food preservative and adjunctive remedy for bacterial food-borne diseases is justified.

Item Description

10.3390/antibiotics11040489
2079-6382