PGE₂ Is Crucial for the Generation of FAST Whole- Tumor-Antigens Loaded Dendritic Cells Suitable for Immunotherapy in Glioblastoma

• Main Authors: Sara Nava (Author), Daniela Lisini (Author), Simona Frigerio (Author), Simona Pogliani (Author), Serena Pellegatta (Author), Laura Gatti (Author), Gaetano Finocchiaro (Author), Anna Bersano (Author), Eugenio Agostino Parati (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dendritic cells (DC) are the most potent antigen-presenting cells, strongly inducers of T cell-mediated immune responses and, as such, broadly used as vaccine adjuvant in experimental clinical settings. DC are widely generated from human monocytes following in vitro protocols which require 5&#87...