Protective effects of Salvianic acid A against multiple-organ ischemia-reperfusion injury: a review

• Main Authors: Shiyu Yang (Author), Heming Chen (Author), Wei Su (Author), Yunchun Luo (Author), Jun Liao (Author), Yun Wang (Author), Liyan Xiong (Author), Chuan Zhang (Author), Fei Li (Author), Zhe-Sheng Chen (Author), Tingfang Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Ischemia-reperfusion (I/R) injury refers to a new injury caused by reperfusion after the restoration of ischemic tissue or organ blood supply. Salvianic acid A (danshensu) is a primary active ingredient extracted from Salvia miltiorrhiza. It has a protective function against I/R injury in the cardiovascular system, brain, liver, kidney, gastrointestinal tract, and other organs. This article reviews evidence of the protective effects of Salvianic acid A and its potential mechanisms of action in organ I/R injury protection. The aim of this review is to investigate the role of Salvianic acid A in the treatment of I/R injury, providing a reference resource that could facilitate subsequent studies.

Item Description

1663-9812
10.3389/fphar.2023.1297124