Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy-A Hypothesis-Driven Review

• Hoofdauteurs: Markus Laube (Auteur), Torsten Kniess (Auteur), Jens Pietzsch (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2016-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients. Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side effects with severe acute and late pathophysiological consequences. Inhibitors of cyclooxygenase-2 (COX-2) are potential...