Generalized hereditary gingival fibromatosis in a child: clinical, histopathological and therapeutic aspects

Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a ge...

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Main Authors: John Lennon Silva Cunha (Author), Maria Alice Carvalho da Cruz Ramos (Author), Débora Menezes Regis (Author), Celeste Sanchéz-Romero (Author), Maria Eliane de Andrade (Author), Bruno Torres Bezerra (Author), Ricardo Luiz Cavalcanti de Albuquerque-Júnior (Author)
Format: Book
Published: University of São Paulo, 2020-01-01T00:00:00Z.
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Summary:Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a generalized gingival enlargement covering almost all the maxillary and mandibular teeth and resulted in problems for swallowing, speaking, and poor aesthetics. An incisional biopsy was performed and revealed a hypocellular and hypovascular dense collagenous tissue covered by squamous epithelium exhibiting acanthosis and elongated rete ridges. The diagnosis was HGF. The treatment instituted was an association of gingivectomy with a rigorous program of oral hygiene and follow-up. Herein, we describe a rare non-syndromic case of generalized HGF, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition.
Item Description:10.4322/acr.2020.140
2236-1960