Power of multifactor dimensionality reduction and penalized logistic regression for detecting gene-gene Interaction in a case-control study

• Autores principales: Brott Marcia J (Autor), Oetting William S (Autor), He Hua (Autor), Basu Saonli (Autor)
• Formato: Libro
• Publicado: BMC, 2009-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>There is a growing awareness that interaction between multiple genes play an important role in the risk of common, complex multi-factorial diseases. Many common diseases are affected by certain genotype combinations (associated with...