Cover Image

Pharmacokinetic-Pharmacometabolomic Approach in Early-Phase Clinical Trials: A Way Forward for Targeted Therapy in Type 2 Diabetes

Pharmacometabolomics in early phase clinical trials demonstrate the metabolic profiles of a subject responding to a drug treatment in a controlled environment, whereas pharmacokinetics measure the drug plasma concentration in human circulation. Application of the personalized peak plasma concentrati...

Full description

Saved in:

Bibliographic Details
Main Authors:	Khim Boon Tee (Author), Luqman Ibrahim (Author), Najihah Mohd Hashim (Author), Mohd Zuwairi Saiman (Author), Zaril Harza Zakaria (Author), Hasniza Zaman Huri (Author)
Format:	Book
Published:	MDPI AG, 2022-06-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Pharmacokinetics in Pharmacometabolomics: Towards Personalized Medication
by: Jingai Jian, et al.
Published: (2023)

Puzzling Techniques: A Way Forward for Mastering the Islamic Finance / Shahsuzan Zakaria...[et al.]
by: Zakaria, Shahsuzan, et al.
Published: (2020)

Development of a Region-Specific Physiologically Based Pharmacokinetic Brain Model to Assess Hippocampus and Frontal Cortex Pharmacokinetics
by: Zaril Zakaria, et al.
Published: (2018)

Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management
by: Nguyen Quang Thu, et al.
Published: (2024)

Pharmacometabolomics Approach to Explore Pharmacokinetic Variation and Clinical Characteristics of a Single Dose of Desvenlafaxine in Healthy Volunteers
by: Anne Michelli Reis Silveira, et al.
Published: (2024)

Pharmacometabolomics of Meglumine Antimoniate in Patients With Cutaneous Leishmaniasis
by: Deninson Alejandro Vargas, et al.
Published: (2019)

Pharmacometabolomics may be the next stamp in the pharmacogenetic passport
by: Frank Klont, et al.
Published: (2024)

Pharmacometabolomics informs viromics towards precision medicine
by: Aggeliki Balasopoulou, et al.
Published: (2016)

Pharmacometabolomics Applied to Personalized Medicine in Urological Cancers
by: Filipa Amaro, et al.
Published: (2022)

Pharmacometabolomics by NMR in Oncology: A Systematic Review
by: Nuria Gómez-Cebrián, et al.
Published: (2021)

In vivo solid phase microextraction for therapeutic monitoring and pharmacometabolomic fingerprinting of lung during in vivo lung perfusion of FOLFOX
by: Nikita Looby, et al.
Published: (2023)

Pharmacometabolomics of trabectedin in metastatic soft tissue sarcoma patients
by: Giuseppe Corona, et al.
Published: (2023)

A temporo-spatial pharmacometabolomics method to characterize pharmacokinetics and pharmacodynamics in the brain microregions by using ambient mass spectrometry imaging
by: Dan Liu, et al.
Published: (2022)

Glycemic effects of simvastatin: Where do we stand?
by: Nor Razida Razali, et al.
Published: (2018)

Solar energy : dilemma and the way forward / Norhafizah Yusop ... [et al.]
by: Norhafizah, Yusop, et al.
Published: (2015)

Unite and team up: The way forward
by: Sangeeta Dhir
Published: (2015)

Post-earthquake Nepal: the way forward
by: Buddha Basnyat, et al.
Published: (2015)

Universal health coverage: The way forward
by: Ashok Kumar Jindal
Published: (2014)

Antenatal anaesthesia clinics - the way forward?
by: Felicity Plaat, et al.
Published: (2018)

Neurodegenerative disorders: The Glia way forward
by: Roger A Barker, et al.
Published: (2014)

Pediatric surgery in India - The way forward
by: Ashley LJ D'Cruz
Published: (2016)

Demographic, clinical and lifestyle predictors for severity of erectile dysfunction and biomarkers level in Malaysian patients
by: Raymond Mark, et al.
Published: (2018)

Clopidogrel Pharmacokinetics in Malaysian Population Groups: The Impact of Inter-Ethnic Variability
by: Zaril H. Zakaria, et al.
Published: (2018)

Beyond binaries : a way forward for comparativeeducation
by: Marianne Larsen
Published: (2012)

Knowledge in the dark: scientific challenges and ways forward
by: Jonathan M. Jeschke, et al.
Published: (2019)

Universal Health Coverage; A Way Forward
by: Nighat Musa
Published: (2022)

Dentistry in Nigeria: past, present and the way forward
by: K. O. Savage
Published: (2010)

Community dermatology: Current status and the way forward
by: Neelakandhan Asokan
Published: (2023)

Hepatocellular carcinoma and aflatoxin in Sudan: The way forward
by: Moawia Mohammed Ali Elhassan
Published: (2024)

Reproductive health and human rights: the way forward
by: Jane Cottingham
Published: (2010)

Evolution of newborn screening in India and the way forward
by: Mukesh Darshan, et al.
Published: (2023)

Managing cleft lip and palate: The way forward
by: Anthony F Markus
Published: (2015)

Contained intra-abdominal morcellation: Is it the way forward?
by: Alexandriia See, et al.
Published: (2016)

Adult vaccination in India: status and the way forward
by: Chandrakant Lahariya, et al.
Published: (2020)

Community medicine in India - Which way forward?
by: Anand Krishnan
Published: (2016)

COVID-19 vaccine development and the way forward
by: Narendra Kumar Arora, et al.
Published: (2020)

Recent developments of acupuncture in Australia and the way forward
by: Zhang Claire, et al.
Published: (2009)

Pharmacometabolomics of sulfonylureas in patients with type 2 diabetes: a cross-sectional study
by: Khaled Naja, et al.
Published: (2024)

Pharmacometabolomics and mass spectrometry imaging approach to reveal the neurochemical mechanisms of Polygala tenuifolia
by: Qian Li, et al.
Published: (2024)

Pharmacometabolomics of Respiratory Phenotypic Response to Dexamethasone in Preterm Infants at Risk for Bronchopulmonary Dysplasia
by: Tamorah Lewis, et al.
Published: (2019)